Shared with you by your Mannatech Associate
The Ambrotose® Family · Multi-Glycan Nutrition

Intelligent immune support. Powered by multi-glycans.*

Our immune system is our internal army, and glycans — complex plant saccharides — can play a major role in optimizing the function of our soldiers, beginning primarily in the gut.* Ambrotose® powder is Mannatech's multi-glycan supplement, built to supply a blend of glycans from four plant sources.*

Ambrotose® Complex powder, 100 g canister
The Four, And Nothing Else
Ambrotose® Complex
Ambrotose LIFE® powder, 100 g canister
The Same Four, Plus Three
Ambrotose LIFE®
30+
Years
Of Mannatech glycan science
4
Glycan Sources
Identical in both formulas
1
Foundation
Manapol® powder at the center of every Ambrotose® formula
Daily
Taken consistently, morning and evening
What Ambrotose® is

Not a vitamin. A different category.

Most supplements supply vitamins and minerals — nutrients the body uses for cellular processes. Ambrotose® supplies something else: glycans, the complex plant saccharides involved in immune-support signaling starting in the gut, beneficial bacterial growth, and in how cells recognize one another and pass signals back and forth.*

“Saccharide” is simply the formal word for sugar, but these are not the sugar in your coffee. Most plant saccharides aren't sweet, and the ones in Ambrotose® are specific structures chosen for their role in immune support, microbiome health, and cellular communication rather than for energy.*

Ambrotose® powder was the first plant-sourced formula designed to deliver a blend of glycans together, from multiple plant sources at once — and it has been made, studied and taken daily for more than thirty years.††

What each source contributes

Aloe vera extract Manapol® powder
Primarily mannose, plus galacturonic acid
Arabinogalactan AmbroGuard® · larch
Galactose and arabinose, plus glucose and mannose
Gum tragacanth Astragalus gummifer
Galactose, arabinose, xylose, fucose, rhamnose and galacturonic acid
Glucosamine vegetarian
An amino glycan the body uses to build other saccharides

The sources overlap on purpose. These glycans also have different structures, and different structures can provide different functions. No single plant supplies the full range, and several saccharides are reinforced by more than one source — which is why the formula uses four rather than one.

Manapol® powder canister
The foundation

Built on the acemannan standard.

At the center of every Ambrotose® formula is Manapol® powder — the standardized, stabilized aloe vera extract grown in the volcanic soils of Costa Rica and hand harvested. Acemannan has a published definition: 1 to 2 million Daltons, set by the Chemical Abstracts Service and USAN. Manapol® powder was built to meet it, and every batch is tested and confirmed.

That matters here because a formula is only as good as what it's built on. The multi-source saccharide base is what makes Ambrotose® a multi-glycan formula — but the aloe underneath it is what makes the whole thing dependable.

A formula is only as good as its foundation.

The four glycan sources

Four plants, chosen for what each one brings.

Both Ambrotose® formulas are built on the same four sources. No single plant in nature supplies the full range of saccharides, so the formula draws on four — each contributing something the others don't.

Manapol®

Aloe vera extract

The standardized, stabilized aloe vera extract at the center of both formulas, grown in the volcanic soils of Costa Rica and hand harvested. Contributes primarily mannose, plus galacturonic acid. Perfectly processed to deliver premium immune support.*

AmbroGuard®

Arabinogalactan powder

Purified arabinogalactan from larch wood. A source of dietary fiber that human colonic bacteria ferment, supporting the growth of beneficial bacteria including bifidobacteria and L. plantarum.*

Astragalus gummifer

Gum tragacanth

A prebiotic fiber from the dried sap of the plant. It contributes glyconutrients — notably the saccharide fucose — and helps support the immune system and cell-to-cell communication.*

Vegetarian

Glucosamine hydrochloride

A plant-sourced amino sugar the body uses as a precursor to manufacture other key saccharides for cellular support, communication and immune function.* Plant-fermented and vegan.

What Ambrotose® supports

Immune support, and what sits behind it.

Both Ambrotose® formulas carry the same approved benefit claims. Nothing below is unique to one or the other.

Scientifically shown to support immune response and cognitive function.*

01

Immune support

Supports a healthy immune system and your body's natural immune response.* May help support your immune system year-round.*

02

Digestive and gut health

A prebiotic dietary supplement that supports the growth of good gut bacteria and helps support proper digestive system function.*

03

Cellular communication

Supports cellular communication.* Around 70% of immune cells reside in the gut, and glycans interact with them.* A blend of plant-sourced polysaccharides.

04

Cognitive function

Supports cognitive function through the gut-brain axis.*

05

Memory and mood

May enhance recall and recognition memory.* May improve mood and decrease irritability.*

Based on a 4 g daily intake¥

06

Daily fiber

Adds to your daily fiber intake — from plant polysaccharides rather than added supplements.

Both Formulas Gluten-free Vegan Vegetarian Kosher Free from dairy and preservatives Made with naturally sourced ingredients
Which formula

Once you know you want Ambrotose®, there's one more question.

Ambrotose® comes in two formulas. They're built on the same four glycan sources and carry the same approved claims — Ambrotose LIFE® powder simply adds three more ingredients alongside those four. Nothing is taken out of either one.

Ambrotose® Complex powder, 100 g canister

The original

Ambrotose® Complex powder

The four glycan sources, and nothing else. Made for more than thirty years, and the formula the Ambrotose® clinical trials were run on directly.††

Shop Ambrotose® Complex
Ambrotose LIFE® powder, 100 g canister

Plus three more

Ambrotose LIFE® powder

The same four sources, plus wakame extract, modified citrus pectin and sodium alginate.

Shop Ambrotose LIFE®

Want the whole comparison? Both ingredient lists, both serving sizes, and every difference between the two formulas, side by side in one table.

Compare the two formulas
Questions people actually ask

The details.

What is Ambrotose®, in one sentence?
A plant-sourced powder that supplies glycans — the complex saccharides that can help to optimize immune function, via the gut microbiome and cellular signaling — from four plant sources, built on Manapol® powder.*
Aren't these just sugars? Will they raise my blood sugar?
Saccharide is the formal name for sugar, but most plant saccharides are not sweet and are not table sugar. Table sugar is a disaccharide; Mannatech does not use it in Ambrotose® powder. The saccharides here are specific plant-sourced structures selected for their role in immune system optimization and cellular communication.*
How is this different from taking Manapol® on its own?
Manapol® powder gives you the standardized aloe vera extract directly. The Ambrotose® family builds on that same Manapol® foundation with a multi-source saccharide base designed to provide a broader spectrum of saccharides used in immune system function and cellular communication.* Many people take both.
Which formula should I start with?
Both are built on the same four glycan sources and carry the same approved claims, so either is a complete starting point. The question is only whether you want the three extra ingredients in Ambrotose LIFE® powder. If you'd like to see every difference side by side, the full comparison is here — or talk to your Mannatech Associate.
How do I take it?
Both formulas are taken twice daily, mixed with food or water. Ambrotose® Complex powder is one rounded 2 g scoop twice daily; Ambrotose LIFE® powder is one level 1.67 g scoop twice daily. Both work through consistent daily use rather than in bursts.
Is it suitable for vegans and people with allergies?
Both formulas are gluten-free, vegan, vegetarian and kosher, and free from dairy and preservatives. Anyone with allergies or sensitivities to an ingredient should consult their personal physician before use. If you are pregnant, nursing, taking medication, have a health condition, or are planning a medical procedure, consult your health professional before use.
How long has Ambrotose® been around?
More than thirty years. Ambrotose® Complex powder is the original formula and the one the Ambrotose® clinical trials were run on directly.††
Mission 5 Million®

Every purchase nourishes a child in need.

Servings of PhytoBlend™ powder are provided to children in need with the purchase of these products.

* These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

The 1–2 million Dalton definition of acemannan was set forth by the Chemical Abstract Service (CAS), a division of the American Chemical Society, and the United States Adopted Names Council (USAN), a division of the American Medical Association.

†† These studies were conducted on Ambrotose® Complex and Advanced Ambrotose® powders. The core technology in these products is the foundation for the Ambrotose LIFE® formulation. Some of the studies were at least partially funded by Mannatech.

¥ Memory, mood, cognitive and well-being claims are based on a 4 g daily intake. In a double-blind, placebo-controlled clinical trial, 4 g daily intake of Ambrotose® Complex powder significantly improved well-being and a positive outlook, and subjects reported improved sleep, increased calmness, concentration and clear-headedness.* Ambrotose® Complex Powder and Ambrotose LIFE® Powder formulas are similar enough to conclude that Ambrotose LIFE® Powder at the 4 g dose will have the same results.

Mannatech, Manapol®, Ambrotose®, Ambrotose LIFE®, AmbroGuard®, PhytoBlend™ and Mission 5 Million® are trademarks of Mannatech, Incorporated.