# Manapol® powder — The Acemannan Standard

> Standardized, stabilized aloe vera extract held to the published definition of acemannan (1–2 million Daltons). Independent analysis by the Complex Carbohydrate Research Center, University of Georgia.

- Page: https://aloe.mannatech.com/manapol/
- Science / substantiation: https://aloe.mannatech.com/manapol/science/
- Shop: https://usa.mannatech.com/shop/manapol
- Publisher: Mannatech, Incorporated (NASDAQ: MTEX)
- Product number: 15601
- Format: powder, 1.05 oz / 30 g canister
- Serving: one scoop (500 mg) mixed with food or water, one to two times daily

## What it is

Manapol® powder is 100% aloe — a standardized, stabilized inner-leaf extract. It is sold on its own and is also the aloe foundation in Ambrotose® Complex powder and Ambrotose LIFE® powder.

Acemannan is not a general term for aloe extract. The Chemical Abstracts Service (CAS) and the United States Adopted Names Council (USAN) define acemannan by molecular weight: 1 to 2 million Daltons.

## Independent results (CCRC, University of Georgia)

Report date 12/06/2022. CCRC code TS111122D. Sample Manapol CRMANE291102. Methods: size exclusion chromatography (SEC) and glycosyl analysis by GC-MS.

- Fraction at 1–2 million Daltons (the acemannan range): ≥43%
- Total polysaccharide content: 67%
- Distinct saccharides detected: 9
- Leading sugar: mannose, 64.7% of the glycosyl profile

Full methods, tables, and report provenance: https://aloe.mannatech.com/manapol/science/llms.txt

## Origin and process

Grown at Natural Aloe de Costa Rica, the only source from which Mannatech buys aloe. Leaves are hand-harvested and hand-filleted. Cold-processed: no heat, no enzymes, no charcoal, no additives, no preservatives. Low in aloins (inner leaf gel only).

## Approved U.S. benefit language (claims basis 13 Dec 2021)

Supports a healthy immune system and the body's natural immune response through its acemannan content. Supports healthy microbiome balance and proper digestive system function. Supports blood lipid and blood sugar levels already in the normal range. Supports cellular communication. Source of glyconutrients; rich in acetylated mannans.

## Clean by formulation

Naturally gluten-free, non-GMO, vegetarian and vegan. No additives, excipients, artificial flavors or colors, preservatives, or MSG. Free of soy, dairy, shellfish, and peanuts. Not irradiated. Low glycemic.

## Related

- Ambrotose® homepage: https://aloe.mannatech.com/llms.txt
- Ambrotose Complex vs Ambrotose LIFE: https://aloe.mannatech.com/ambrotose/llms.txt
- Science page: https://aloe.mannatech.com/manapol/science/llms.txt

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.